The Science Behind Kanna's Feel-Good Effects

For centuries, South African tribes turned to Kanna (Sceletium tortuosum) to calm the mind, lift the spirit and strengthen social connection.

Today, science is finally catching up — revealing how this humble succulent works within the body to create that distinct sense of calm focus and emotional uplift.

At Bush Doctor, we honour this ancient plant by combining traditional wisdom with modern scientific understanding.

1. Kanna and the Serotonin System

Kanna naturally supports the body's serotonin pathways — the same network responsible for regulating mood, motivation, and social confidence.

Research shows that its primary alkaloids, mesembrine and mesembrenone, act as selective serotonin reuptake inhibitors (SSRIs) — but in a gentler, plant-based form.

This means serotonin remains active in the brain longer, promoting a balanced, steady sense of wellbeing without overstimulation.

2. Stress Response and Cortisol Balance

Studies suggest Kanna helps reduce cortisol, the body's main stress hormone.

By moderating cortisol levels, it supports a calmer nervous system and improved focus under pressure. Many users report that instead of dulling emotions, Kanna helps them feel more centred and composed — even in demanding environments.

3. Enhanced Cognitive Function

Beyond mood, Kanna may also support mental clarity and memory. Some early research points to improved executive function — the brain's ability to plan, concentrate, and manage emotions — making it a valuable ally for modern multitaskers.

4. Social Connection and Emotional Balance

Traditionally, Kanna was used during gatherings and ceremonies to promote openness and community.

This aligns with what users describe today: enhanced sociability, reduced anxiety, and greater ease in conversation. It's not about euphoria — it's about feeling at ease within yourself and with others.

5. Modern Research and Quality

Modern clinical trials continue to explore Kanna's role as a natural mood modulator. At Bush Doctor, we source standardized extracts to ensure consistent levels of key active compounds, so you experience reliable effects every time — naturally, safely and responsibly.

Bush Doctor's Commitment to Science and Tradition

Our KANNA Series — Calm. Focus. Boost. captures the harmony between traditional use and scientific innovation.

Each formula is designed to help you manage stress, sharpen focus, and uplift your mood — backed by nature and refined by science.